Adderall (for ADHD contains amphetamine) - Wikipedia
[nb: also taken recreationally]Adderall is a psychostimulant medication that contains amphetamine, used for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.[1]
Adderall is a combination of four amphetamine salts (racemic amphetamine aspartate monohydrate, racemic amphetamine sulfate, dextroamphetamine saccharide, and dextroamphetamine sulfate). It is a dopamine releasing agent, a norepinephrine releasing agent, and can be mildly serotonergic.[2]
It is available in two formulations: IR (Instant Release) and XR (Extended Release). The immediate release formulation is indicated for use in ADHD and narcolepsy,[3] while the XR formulation is approved for use only with attention deficit hyperactivity disorder (ADHD).[2]
Like other stimulant drugs, such as methamphetamine and cocaine, Adderall directly affects the mesolimbic reward pathway in the brain. Amphetamine salt preparations are considered to have high abuse potential, and it is classified as Schedule II by the US DEA. With the Safe Streets and Communities Act in Canada, Adderall has been reclassified from Schedule III to Schedule I.[5]
Contents
- 1 Medical uses
- 2 Adverse effects
- 3 Chemistry
- 4 Metabolism
- 5 Generic forms
- 6 Mechanism of action
- 7 Performance-enhancing use
- 8 Recreational use
- 9 History
- 10 Legal status
- 11 References
 | |
|---|---|
| Combination of | |
| Dextroamphetamine | Psychostimulant |
| Amphetamine | Psychostimulant |
| Clinical data | |
| Trade names | Adderall Adderall ER Adderall XR |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a601234 |
| Licence data | US Daily Med:link |
| Pregnancy cat. | C (US) |
| Legal status | Schedule I (CA) Schedule II (US) |
| Dependence liability | High |
| Routes | (Medical) Oral, (Recreational) Oral, Insufflated, Intravenous |
