Piperine - Wikipedia, the free encyclopedia
By inhibiting certain enzyme metabolism, piperine may alter the effectiveness of certain medications by increasing the bioavailability of various compounds.[16]
Notably, piperine may enhance bioavailability of curcumin by 2000% in humans.[18] Chemopreventive efficacy of curcumin and piperine has been shown during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.[19]
Piperine may enhance the pharmacokinetic parameters of resveratrol via inhibiting glucuronidation, thereby slowing its metabolism.[20]
In February 2008, researchers discovered that piperine can stimulate pigmentation in the skin, together with the exposure to UVB light.[21][22]
Piperine has shown 'anti-depression like activity', and cognitive enhancing effects in rats.[23]
Piperine has shown anti-inflammatory and anti-arthritic effects in human interleukin-1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models.[24]
Piperine also possesses anti-angiogenic activities.[25]
By inhibiting certain enzyme metabolism, piperine may alter the effectiveness of certain medications by increasing the bioavailability of various compounds.[16]
Notably, piperine may enhance bioavailability of curcumin by 2000% in humans.[18] Chemopreventive efficacy of curcumin and piperine has been shown during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.[19]
Piperine may enhance the pharmacokinetic parameters of resveratrol via inhibiting glucuronidation, thereby slowing its metabolism.[20]
In February 2008, researchers discovered that piperine can stimulate pigmentation in the skin, together with the exposure to UVB light.[21][22]
Piperine has shown 'anti-depression like activity', and cognitive enhancing effects in rats.[23]
Piperine has shown anti-inflammatory and anti-arthritic effects in human interleukin-1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models.[24]
Piperine also possesses anti-angiogenic activities.[25]
