Wednesday 18 September 2013

Studies on gut bacteria and psychological function - probiotic drinks

Source: I've Got A [Gut] Feeling, But I'm Not Going to EatAnything | Free The Animal

EXPERTS ARE CONVINCED THAT TWEAKING THESE BACTERIA LATER IN LIFE CAN YIELD PROFOUND BEHAVIORAL AND PSYCHOLOGICAL CHANGES
It’s a distinct possibility: in one 2013 proof-of-concept study, researchers at UCLA showed that healthy women who consumed a drink with four added probiotic strains twice daily for four weeks showed significantly altered brain functioning on an fMRI brain scan. The women’s brains were scanned while they looked at photos of angry or sad faces, and then asked to match those with other faces showing similar emotions.
Those who had consumed the probiotic drink showed significantly lower brain activity in the neural networks that help drive responses to sensory and emotional behavior. The research is “groundbreaking,” Cryan said, because it’s the first trial to show that probiotics could affect the functioning of the human brain. Still, he notes that the results need to be interpreted with care.

As the research community increasingly lends credence to Greenblatt’s ideas, and public awareness about gut bacteria grows, he’s confident we’ll soon know more about the power of probiotics. “Because of the commercials and the other information that’s out there, patients are beginning to ask,” he said. “They’re much more aware of how important probiotics are.”
 Another example:
Her parents were running out of hope. Their teenage daughter, Mary, had been diagnosed with a severe case of obsessive–compulsive disorder (OCD), as well as ADHD. They had dragged her to clinics around the country in an effort to thwart the scary, intrusive thoughts and the repetitive behaviors that Mary felt compelled to perform. Even a litany of psychotropic medications didn’t make much difference. It seemed like nothing could stop the relentless nature of Mary’s disorder.

Their last hope for Mary was Boston-area psychiatrist James Greenblatt. Arriving at his office in Waltham, MA, her parents had only one request: help us help Mary.
Greenblatt started by posing the usual questions about Mary’s background, her childhood, and the onset of her illness. But then he asked a question that no psychiatrist ever had: How was Mary’s gut? Did she suffer digestive upset? Constipation or diarrhea? Acid reflux? Had Mary’s digestion seemed to change at all before or during her illness? Her parents looked at each other.

The answer to many of the doctor’s questions was, indeed, “Yes.”

That’s what prompted Greenblatt to take a surprising approach: besides psychotherapy and medication, Greenblatt also prescribed Mary a twice-daily dose of probiotics, the array of helpful bacteria that lives in our gut. The change in Mary was nothing short of miraculous: within six months, her symptoms had greatly diminished. One year after the probiotic prescription, there was no sign that Mary had ever been ill.
Her parents may have been stunned, but to Greenblatt, Mary’s case was an obvious one. An imbalance in the microbes in Mary’s gut was either contributing to, or causing, her mental symptoms. “The gut is really your second brain,” Greenblatt said. “There are more neurons in the GI tract than anywhere else except the brain.” [...]